Incorporation of 3-Aminobenzanthrone into 2′-Deoxyoligonucleotides and Its Impact on Duplex Stability
Figure 3
Expanded contour plot showing the finger print region of a 300 ms mixing time NOESY spectrum (600 MHz) of the 14-mer dG(N 2)-3ABA duplex dissolved in 100% D2O phosphate buffer, pH 6.9. The labels identify cross-peaks between the purine(H8), or pyrimidine(H6), and the H1′ sugar proton of the same residue. Asterisks indicate cytosine(H5-H6) interactions. Other labels are assigned as follows: A, 3ABA(H2)-G5(H1′); B, 3ABA(H3)-G5(H1′); C, 3ABA(H3)-T12(H1′). The arrow points to the position of C6(H1′) that resonates outside of the plotted region, at 4.43 ppm.
