Research Article

Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4

Figure 2

Melting temperature dependence on concentration of oligonucleotide. A linear dependence of TM with strand concentration demonstrates that the G-quadruplex formed is intramolecular. Filled squares are TM from UV melting curves, filled circle is TM from DSC and filled triangle is TM from CD.
529828.fig.002