Research Article

Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4

Figure 6

Effect of TMPyP4 and RPA on Gq23 in the presence of Na+ ions. (a) CD spectra of Gq23 at a 1 : 5 molar ratio of Gq23 : TMPyP4 (black line). Spectra were collected upon addition of increasing molar ratios (0–5) of RPA or (b) RPA-CDE-core. All spectra were recorded in a buffer containing 100 mM NaCl.
529828.fig.006a
(a)
529828.fig.006b
(b)