Branched RNA: A New Architecture for RNA Interference

<table>HPLC profile of DMT-containing oligonucleotide <b>2</b> with two arms. Truncated sequences without DMT groups had a retention of less than 5 min. Fraction eluting between 7-8 min contained oligonucleotides with a single DMT group. The last fraction contained the desired sequence with two DMT groups.</table>

Journal of Nucleic Acids

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Figure 4

Figure 4: Branched RNA: A New Architecture for RNA Interference 