Research Article

Branched RNA: A New Architecture for RNA Interference

Figure 5

HPLC purification of oligonucleotide 3 with four arms. (a) HPLC profile of DMT-containing oligonucleotide 3. The last fraction contained the desired sequence with four DMT groups; (b) analytical HPLC of purified oligonucleotide 3 after removal of DMT groups.
586935.fig.005a
(a)
586935.fig.005b
(b)