Site-Selective Artificial Ribonucleases: Oligonucleotide Conjugates Containing Multiple Imidazole Residues in the Catalytic Domain
Figure 5
A fragment of the most favourable conformation, F4-Im(4/1), found for hybrid complex H- Im(4/1) between artificial ribonuclease B-Im(4/1) and tRNAPhe where the close proximity of imidazole cleaving groups to the target sequence C63-A64 (green) is evident. Hydrogen bonds are shown in yellow.