Radiolytic Reduction Characteristics of Artificial Oligodeoxynucleotides Possessing 2-Oxoalkyl Group or Disulfide Bonds

Figure 2

(a) Radiation-activated prodrugs of 5-flurouracil (1–4) and 2′-deoxy-5-fluorouridine (5–7) possessing 2-oxoalkyl groups. (b) Plausible mechanism for reductive release of 2-oxoalkyl group.

(a)

(b)