Radiolytic Reduction Characteristics of Artificial Oligodeoxynucleotides Possessing 2-Oxoalkyl Group or Disulfide Bonds
Figure 4
Design of caged DNAzyme activated by X-irradiation. (a) Schematic illustration of radiolytic activation of DNAzyme possessing 2-oxoalkyl group. (b) Fluorescence spectra of ODN 4 (500 nM) after addition of Zn2+ ion (100 μM) and X-irradiated (0, 20 and 40 Gy) ODN 3 (500 nM) under hypoxic conditions.
