The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

Figure 3

Normalized UV melting curves for 20 μM AP-0 (a), AP-1 (b), AP-2 (c), and AP-3 (d) in a buffer of 100 mM NaCl, 50 mM Tris-HCl (pH 7.0), and 1 mM Na₂EDTA at 0 wt% (0 mol L⁻¹) (solid line) and 40 wt% (2 mol L⁻¹) (dashed line) PEG200.

(a)

(b)

(c)

(d)