The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

Figure 4

Plots of ln 𝐾_obs versus ln𝑎_𝑤 for AP-0 (closed circle) and AP-1 (open circle) for the formation of the G-quadruplex in a buffer of 100 mM NaCl, 50 mM Tris-HCl (pH 7.0), and 1 mM Na₂EDTA containing 0 (0 mol L⁻¹), 10 (0.5 mol L⁻¹), 20 (1 mol L⁻¹), 30 (1.5 mol L⁻¹), or 40 (2 mol L⁻¹) wt% PEG200 at 37°C.