Use of Nucleic Acid Analogs for the Study of Nucleic Acid Interactions
Figure 5
(a) Stacking conformations of the dangling and (colored in red) at the 5′-end of a DNA duplex. (b) Side view of the DNA double helix, representing the interaction mechanism of the dangling end stacking (upper) and the Watson-Crick base pairing (lower). Cooperative interaction in the base pair-mimic nucleoside is suggested between stacking of the base moiety and stacking of the nonpolar group.
