Journal of Nucleic Acids / 2012 / Article / Tab 1

Review Article

Dioxaphosphorinane-Constrained Nucleic Acid Dinucleotides as Tools for Structural Tuning of Nucleic Acids

Table 1

Summary of the backbone torsion angles derived from the canonical BI-, A-DNA duplex structures and of the synthesized D-CNAa.

NameIsomerTorsion angles

BI-typegtg+a+/ttg/a
A-typegtg+g+/a+a/tg
-D-CNA( )gt
( )g+t
( )a+a/t
( ) aa+/t
-P-CNA( )g+t
( ) a/tt
LNA/ -D-CNA( )gtg+/a+
( )g+tg+/a+
( ) a+a/tg+/a+
-D-CNAcis ggg
trans g+c/g+g/a
-D-CNA( )a+/tgg
( ) a+/tga+/t
-D-CNA( )a+g+g
( ) a+g+t
-D-CNA( )ctg+
( )ctg

aThe following 6-fold staggered pattern of the torsional angles is used: cis: 0 ± 30° (c), gauche (+) = 60 ± 30° (g+), anticlinal (+): 120 ± 30° (a+), trans: 180 ± 30° (t), anticlinal (−) = 240 ± 30° (a), and gauche (−) = 300 ± 30° (g). The notation a+/t is used to designate a torsion angle on the border of anticlinal (+) and trans.

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