Nucleic-Acid-Binding Chromophores as Efficient Indicators of Aptamer-Target Interactions

Table 1

Sequences of aptamers used and their affinities for corresponding target.

Target	Sequence	Affinity (𝐾𝑑)	Expected secondary structure
ATP [17]	5′-ATAGCGGAGGAAGGATACCTGGGGGAGTATAT-3′	6 μM	Quadruplex, stem-loop
Thrombin [18]	5′-GGTTGGTGTGGTTGG-3′	10 nM	Quadruplex
Theophylline [21]	5′-GGUGAUACCAGCAUCGUCUUGAUGCCCUUGGCAGCACC-3′	220 nM	Hairpin, stem-loop