Superior Silencing by 2′,4′-BNA^NC-Based Short Antisense Oligonucleotides Compared to 2′,4′-BNA/LNA-Based Apolipoprotein B Antisense Inhibitors

Figure 1

Structures of the BNAs. The chemical structure on the left is the original BNA, 2′,4′-BNA/LNA, and the structure on the right is 2′,4′-BNA^NC.