Research Article

Thermodynamic and Structural Analysis of DNA Damage Architectures Related to Replication

Figure 4

CD spectra comparing the effect of 3 on the secondary structure of replication relevant architectures. The top row shows the CD spectra for constructs of Sequence 1 (solid lines), while the bottom row shows the CD spectra for Sequence 2 (dashed lines). Constructs containing unmodified oligomers are represented in blue, while the constructs containing 3 are in black. (a) duplexes, (b) 5′ and 3′ OvHgs, (c) fork.
867957.fig.004a
(a) dsDNA 
867957.fig.004b
(b) OvHg
867957.fig.004c
(c) Fork