Journal of Nucleic Acids / 2016 / Article / Tab 1

Research Article

Copy Number Variation of UGT 2B Genes in Indian Families Using Whole Genome Scans

Table 1

Functional annotation of proteins, their significant value, and the number of genes participating in the UGT2B17, UGT2B15, and UGT2B28 mediated steroid metabolism and glucuronidation pathways.

SymbolEntrez Gene NameLocationType(s)Biomarker Application(s)

ABCG1ATP-binding cassette, subfamily G (white), member 1Plasma membraneTransporterUnspecified application
AndrogenOtherChemical, other
AndrosteroneOtherChemical, endogenous mammalian
C/ebpCytoplasmGroup
DiclofenacOtherChemical drug
DihydrotestosteroneOtherChemical, endogenous mammalianDiagnosis, efficacy
ELF5E74-like factor 5 (ets domain transcription factor)NucleusTranscription regulator
FluconazoleOtherChemical drug
FOXA1Forkhead box A1NucleusTranscription regulatorDisease progression
HNF1BHNF1 homeobox BNucleusTranscription regulator
IbuprofenOtherChemical drug
KLK3Kallikrein-related peptidase 3Extracellular spacePeptidaseDiagnosis, disease progression, efficacy, safety, and unspecified application
KLK4Kallikrein-related peptidase 4Extracellular spacePeptidaseDiagnosis, efficacy
Methylseleninic acidOtherChemical reagent
miR-619-3p (miRNAs w/seed ACCUGGA)CytoplasmMature microRNA
NKX3-1NK3 homeobox 1NucleusTranscription regulator
ONECUT1One cut homeobox 1NucleusTranscription regulator
PhenobarbitalOtherChemical drug
ProgestinOtherChemical, other
RAD23ARAD23 homolog A (S. cerevisiae)NucleusOther
SLC16A6Solute carrier family 16, member 6 (monocarboxylic acid transporter 7)Plasma membraneTransporter
SLC25A13Solute carrier family 25 (aspartate/glutamate carrier), member 13CytoplasmTransporter
SLC9A3Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3Plasma membraneIon channelUnspecified application
TestosteroneOtherChemical, endogenous mammalianDiagnosis, efficacy, prognosis, safety
TMPRSS2Transmembrane protease, serine 2Plasma membranePeptidase
trans-3′-hydroxycotinine-glucuronideOtherChemical reagent
UGT1A1UDP glucuronosyltransferase 1 family, polypeptide A1CytoplasmEnzymeDiagnosis, efficacy
UGT2B15UDP glucuronosyltransferase 2 family, polypeptide B15CytoplasmEnzyme
UGT2B17UDP glucuronosyltransferase 2 family, polypeptide B17CytoplasmEnzyme
UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28CytoplasmOther