Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers

Figure 9

Binding of Cy3 dye to a variety of G-quartet and non-G-quartet aptamer sequences using (a) initial RF aptamer selection buffer; (b) PBSMTB without K⁺. Error bars represent SEM of raw fluorescence intensity values for 5–15 replicates of each sequence. Linker identity was T unless otherwise specified.

(a)

(b)