On the Helical Structure of Guanosine 5′-Monophosphate Formed at pH 5: Is It Left- or Right-Handed?

Figure 1

Contrasting physical appearance of 1.0 M Na₂(5′-GMP) aqueous solution at pH 8 (a) and pH 5 (b) and the two structural motifs responsible for the 5′-GMP self-assembly: (c) planar G-quartet (disc-G₄) and (d) open-ended G-quartet (lock-washer-G₄).

(a)

(b)

(c)

(d)