Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA Damage

<div>PCNA is important to the gap-filling during the repair of UV-induced DNA injuries and is also essential to the repair of oxidative DNA lesions. When oxidative DNA damage increases or XRCC1 overexpresses, more PCNA is recruited to BER, which may leave more gaps unfilled.</div>

Journal of Nucleic Acids

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Figure 9

Figure 9: Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA Damage 