A Sequence-Dependent DNA Condensation Induced by Prion Protein

<div>Dependence of fluorescence quenching of gcDNA bound YOYO with varying dye to DNA molar ratio in the presence of increasing <i>α</i>-PrP concentrations. (a) Titration with dye : DNA-ph = 1 : 50 and (b) with dye : DNA-ph = 1 : 2000. Therefore dye : DNA-ph ratio = 1 : 2000 used for the acrylamide accessibility experiments.</div>

Journal of Nucleic Acids

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Figure 9

Figure 9: A Sequence-Dependent DNA Condensation Induced by Prion Protein 