Journal of Neurodegenerative Diseases / 2013 / Article / Fig 2

Research Article

Neuroprotection by Exendin-4 Is GLP-1 Receptor Specific but DA D3 Receptor Dependent, Causing Altered BrdU Incorporation in Subventricular Zone and Substantia Nigra

Figure 2

Effect of 0.5 μg kg−1 EX-4 alone or in the presence of EX-9-39 or NAF on striatal tissue DA. Both antagonists were coadministered with EX-4 twice daily for seven days, one week after toxin injection. Results were analyzed using one-way ANOVA ( ; ) and a post hoc Bonferroni test to compare differences between groups. Results were analyzed using one-way ANOVA ( ; ) and a post hoc Bonferroni test to compare differences between groups. * compared to 6-OHDA, 6-OHDA + EX-4 + EX-(3-39), and 6-OHDA + EX-4 + NAF groups; ** compared to shams, 6-OHDA, 6-OHDA + EX-4, EX-4, EX-(9-39), and NAF.
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