Sex Differences in Presynaptic Density and Neurogenesis in Middle-Aged ApoE4 and ApoE Knockout Mice
Figure 4
Neurogenesis in the dentate gyrus of the hippocampus. In female mice, a trend was observed in the number of doublecortin-positive newly formed neurons between genotypes ( = 6–7 mice/group, #). The data strongly indicate that neurogenesis is increased in female apoE knockout mice compared with female wild-type mice. In males, no differences in neurogenesis were found ( = 5–7 mice/group, ). Error bars show mean ± SEM.
