Table of Contents
Journal of Neurodegenerative Diseases
Volume 2014 (2014), Article ID 359436, 9 pages
http://dx.doi.org/10.1155/2014/359436
Research Article

Nicotine-Cadmium Interaction Alters Exploratory Motor Function and Increased Anxiety in Adult Male Mice

1Department of Physiology, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria
2Department of Anatomy, Cell Biology and Neuroscience Unit, College of Medicine and Health Sciences, Afe Babalola University, College Building II, Room G14, Km 8.5 Afe Babalola Way, PMB 5454, Ado-Ekiti, Ekiti State, Nigeria
3Department of Biological Sciences, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria
4Department of Anatomy, College of Health Sciences, University of Ilorin, Ilorin, Kwara State, Nigeria

Received 17 May 2014; Accepted 27 August 2014; Published 13 November 2014

Academic Editor: Yasuji Matsuoka

Copyright © 2014 Duyilemi Chris Ajonijebu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. Robertson, R. McGee, and R. J. Hancox, “Smoking cessation and subsequent weight change,” Nicotine & Tobacco Research, 2014. View at Google Scholar
  2. A. Stanton and G. Grimshaw, “Tobacco cessation interventions for young people,” The Cochrane Database of Systematic Reviews, vol. 8, Article ID CD003289, 2013. View at Google Scholar · View at Scopus
  3. S. E. Jones and S. Hamilton, “Introducing a new stop smoking service in an acute UK hospital: a qualitative study to evaluate service user experience,” European Journal of Oncology Nursing, vol. 17, no. 5, pp. 563–569, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Raupach, P. H. J. Hoogsteder, and C. P. O. van Schayck, “Nicotine vaccines to assist with smoking cessation: current status of research,” Drugs, vol. 72, no. 4, pp. e1–e16, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. H. S. Menossi, A. E. Goudriaan, C. D. A.-M. Périco et al., “Neural bases of pharmacological treatment of nicotine dependence—insights from functional brain imaging: a systematic review,” CNS Drugs, vol. 27, no. 11, pp. 921–941, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Zhang, K. Hyrc, S. Wang, and B. M. Wice, “Xenin-25 increases cytosolic free calcium levels and acetylcholine release from a subset of myenteric neurons,” The American Journal of Physiology: Gastrointestinal and Liver Physiology, vol. 303, no. 12, pp. G1347–G1355, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. N. da Silva, C. E. Herron, K. Stevens, C. A. B. Jollimore, S. Barnes, and M. E. Kelly, “Metabotropic receptor-activated calcium increases and store-operated calcium influx in mouse Müller cells,” Investigative Ophthalmology and Visual Science, vol. 49, no. 7, pp. 3065–3073, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Wang, W. Sun, J. Ma, Y. Pan, L. Wang, and W. Zhang, “Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of intracellular calcium and Akt/β-catenin pathway,” PLoS ONE, vol. 9, no. 3, Article ID e91730, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. S. N. Grishin, R. R. Kamaliev, A. Y. Teplov, and A. U. Ziganshin, “Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs,” Bulletin of Experimental Biology and Medicine, vol. 151, no. 3, pp. 280–283, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. Y.-M. Yang and G.-T. Liu, “Damaging effect of cigarette smoke extract on primary cultured human umbilical vein endothelial cells and its mechanism,” Biomedical and Environmental Sciences, vol. 17, no. 2, pp. 121–134, 2004. View at Google Scholar · View at Scopus
  11. D. Pogocki, T. Ruman, M. Danilczuk, M. Celuch, and E. Wałajtys-Rode, “Application of nicotine enantiomers, derivatives and analogues in therapy of neurodegenerative disorders,” European Journal of Pharmacology, vol. 563, no. 1–3, pp. 18–39, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Miura, D. Yuki, N. Minami, A. Kakehi, and M. Onozawa, “Pharmacokinetic analysis of nicotine when using non-combustion inhaler type of tobacco product in Japanese adult male smokers,” Regulatory Toxicology and Pharmacology, vol. 67, no. 2, pp. 198–205, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. X. M. Shao, B. Xu, J. Liang, X. Xie, Y. Zhu, and J. L. Feldman, “Nicotine delivery to rats via lung alveolar region-targeted aerosol technology produces blood pharmacokinetics resembling human smoking,” Nicotine and Tobacco Research, vol. 15, no. 7, pp. 1248–1258, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. M. A. Babizhayev, “The detox strategy in smoking comprising nutraceutical formulas of non-hydrolyzed carnosine or carcinine used to protect human health,” Human and Experimental Toxicology, vol. 33, no. 3, pp. 284–316, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Storage, M. A. Mandelkern, J. Phuong, M. Kozman, M. K. Neary, and A. L. Brody, “A positive relationship between harm avoidance and brain nicotinic acetylcholine receptor availability,” Psychiatry Research, vol. 214, no. 3, pp. 415–421, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. E. Kleszczewska, J. Hejza, and T. Kleszczewski, “Determination of cadmium level in passive tobacco smokers schizophrenia patients,” Przegla̧d Lekarski, vol. 63, no. 10, pp. 998–1001, 2006. View at Google Scholar · View at Scopus
  17. P. Checconi, R. Sgarbanti, I. Celestino et al., “The environmental pollutant cadmium promotes influenza virus replication in MDCK cells by altering their redox state,” International Journal of Molecular Sciences, vol. 14, no. 2, pp. 4148–4162, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. M. González-Estecha, E. Trasobares, M. Fuentes et al., “Blood lead and cadmium levels in a six hospital employee population. PESA study, 2009,” Journal of Trace Elements in Medicine and Biology, vol. 25, supplement 1, pp. S22–S29, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. M. E. Culbreth, J. A. Harrill, T. M. Freudenrich, W. R. Mundy, and T. J. Shafer, “Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells,” NeuroToxicology, vol. 33, no. 6, pp. 1499–1510, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Kurata, O. Katsuta, T. Doi et al., “Chronic cadmium treatment induces tubular nephropathy and osteomalacic osteopenia in ovariectomized cynomolgus monkeys,” Veterinary Pathology, vol. 51, no. 5, pp. 919–931, 2013. View at Publisher · View at Google Scholar
  21. Y.-F. Song, Z. Luo, Y.-X. Pan, X. Liu, C. Huang, and Q.-L. Chen, “Effects of copper and cadmium on lipogenic metabolism and metal element composition in the javelin goby (Synechogobius hasta) after single and combined exposure,” Archives of Environmental Contamination and Toxicology, vol. 67, no. 2, pp. 167–180, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Haouem and A. El Hani, “Effect of cadmium on lipid peroxidation and on some antioxidants in the liver, kidneys and testes of rats given diet containing cadmium-polluted radish bulbs,” Journal of Toxicologic Pathology, vol. 26, no. 4, pp. 359–364, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. B. Wang and Y. Du, “Cadmium and its neurotoxic effects,” Oxidative Medicine and Cellular Longevity, vol. 2013, Article ID 898034, 12 pages, 2013. View at Publisher · View at Google Scholar
  24. K. P. Timms, D. E. Rivera, L. M. Collins, and M. E. Piper, “A dynamical systems approach to understanding self-regulation in smoking cessation behavior change,” Nicotine and Tobacco Research, vol. 16, no. 2, pp. S159–S168, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. E. A. Kiyatkin, “Critical role of peripheral sensory systems in mediating the neural effects of nicotine following its acute and repeated exposure,” Review of Neuroscience, vol. 25, no. 2, pp. 207–221, 2014. View at Google Scholar
  26. S. P. Barrett and C. Darredeau, “The acute effects of nicotine on the subjective and behavioural responses to denicotinized tobacco in dependent smokers,” Behavioural Pharmacology, vol. 23, no. 3, pp. 221–227, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. S. E. Santiago and K. J. Huffman, “Prenatal nicotine exposure increases anxiety and modifies sensorimotor integration behaviors in adult female mice,” Neuroscience Research, vol. 79, no. 1, pp. 41–51, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. H. Yamada, M. Bishnoi, K. F. M. Keijzers et al., “Preadolescent tobacco smoke exposure leads to acute nicotine dependence but does not affect the rewarding effects of nicotine or nicotine withdrawal in adulthood in rats,” Pharmacology Biochemistry and Behavior, vol. 95, no. 4, pp. 401–409, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. J. Wu, M. Gao, J. X. Shen, W. X. Shi, A. M. Oster, and B. S. Gutkin, “Cortical control of VTA function and influence on nicotine reward,” Biochemical Pharmacology, vol. 86, no. 8, pp. 1173–1180, 2013. View at Publisher · View at Google Scholar
  30. J. Ren, J. Sun, Y. Zhang et al., “Down-regulation of Decapping Protein 2 mediates chronic nicotine exposure-induced locomotor hyperactivity in Drosophila,” PLoS ONE, vol. 7, no. 12, Article ID e52521, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. B. N. Cohen, E. D. W. Mackey, S. R. Grady et al., “Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior,” Neuroscience, vol. 200, pp. 31–41, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. C. V. Abobo, J. Ma, and D. Liang, “Effect of menthol on nicotine pharmacokinetics in rats after cigarette smoke inhalation,” Nicotine and Tobacco Research, vol. 14, no. 7, pp. 801–808, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. M. Sofuoglu, A. I. Herman, H. Nadim, and P. Jatlow, “Rapid nicotine clearance is associated with greater reward and heart rate increases from intravenous nicotine,” Neuropsychopharmacology, vol. 37, no. 6, pp. 1509–1516, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. Z. X. Xi, K. Spiller, and E. L. Gardner, “Mechanism-based medication development for the treatment of nicotine dependence,” Acta Pharmacologica Sinica, vol. 30, no. 6, pp. 723–739, 2009. View at Publisher · View at Google Scholar
  35. A. C. Harris, C. Mattson, D. Shelley, and M. G. LeSage, “Restraint stress attenuates nicotine 's locomotor stimulant but not discriminative stimulus effects in rats,” Pharmacology Biochemistry and Behavior, vol. 124, pp. 92–100, 2014. View at Publisher · View at Google Scholar
  36. F. Panin, A. Lintas, and M. Diana, “Nicotine-induced increase of dopaminergic mesoaccumbal neuron activity is prevented by acute restraint stress. In vivo electrophysiology in rats,” European Neuropsychopharmacology, vol. 24, no. 7, pp. 1175–1180, 2014. View at Publisher · View at Google Scholar · View at Scopus
  37. K. Łukawski, B. Nieradko, and M. Sieklucka-Dziuba, “Effects of cadmium on memory processes in mice exposed to transient cerebral oligemia,” Neurotoxicology and Teratology, vol. 27, no. 4, pp. 575–584, 2005. View at Publisher · View at Google Scholar · View at Scopus
  38. United States Environmenatl Protection Agency, “Acute exposure guide line level for cadmium,” 2014, http://www.epa.gov/oppt/aegl/pubs/rest303.html.
  39. M. Mesfin, K. Asres, and W. Shibeshi, “Evaluation of anxiolytic activity of the essential oil of the aerial part of Foeniculum vulgare Miller in mice,” BMC Complementary and Alternative Medicine, vol. 14, no. 1, p. 310, 2014. View at Publisher · View at Google Scholar
  40. S. Döker, M. Hazar, M. Uslu, İ. Okan, E. Kafkas, and I. I. Boşgelmez, “Influence of training frequency on serum concentrations of some essential trace elements and electrolytes in male swimmers,” Biological Trace Element Research, vol. 158, no. 1, pp. 15–21, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. A. V. Ivanina, E. P. Sokolov, and I. M. Sokolova, “Effects of cadmium on anaerobic energy metabolism and mRNA expression during air exposure and recovery of an intertidal mollusk Crassostrea virginica,” Aquatic Toxicology, vol. 99, no. 3, pp. 330–342, 2010. View at Publisher · View at Google Scholar · View at Scopus
  42. H. Lu, G. Yuan, Z. Yin et al., “Effects of subchronic exposure to lead acetate and cadmium chloride on rat's bone: Ca and Pi contents, bone density, and histopathological evaluation,” International Journal of Clinical and Experimental Pathology, vol. 7, no. 2, pp. 640–647, 2014. View at Google Scholar · View at Scopus
  43. V. Prabhakar, G. Jayakrishnan, S. V. Nair, and B. Ranganathan, “Determination of trace metals, moisture, pH and assessment of potential toxicity of selected smokeless tobacco products,” Indian Journal of Pharmaceutical Sciences, vol. 75, no. 3, pp. 262–269, 2013. View at Publisher · View at Google Scholar · View at Scopus
  44. B. Bodereau-Dubois, O. List, D. Calas-List et al., “Transmembrane potential polarization, calcium influx, and receptor conformational state modulate the sensitivity of the imidacloprid-insensitive neuronal insect nicotinic acetylcholine receptor to neonicotinoid insecticides,” Journal of Pharmacology and Experimental Therapeutics, vol. 341, no. 2, pp. 326–339, 2012. View at Publisher · View at Google Scholar · View at Scopus
  45. M. F. Borgerding, J. A. Bodnar, G. M. Curtin, and J. E. Swauger, “The chemical composition of smokeless tobacco: a survey of products sold in the United States in 2006 and 2007,” Regulatory Toxicology and Pharmacology, vol. 64, no. 3, pp. 367–387, 2012. View at Publisher · View at Google Scholar · View at Scopus
  46. N. B. Kroemer, A. Guevara, S. Vollstädt-Klein, and M. N. Smolka, “Nicotine alters food-cue reactivity via networks extending from the hypothalamus,” Neuropsychopharmacology, vol. 38, no. 11, pp. 2307–2314, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. A. P. Varani and G. N. Balerio, “GABAB receptors involvement in the effects induced by nicotine on anxiety-related behaviour in mice,” Pharmacological Research, vol. 65, no. 5, pp. 507–513, 2012. View at Publisher · View at Google Scholar · View at Scopus
  48. S. D. Iñiguez, B. L. Warren, E. M. Parise et al., “Nicotine exposure during adolescence induces a depression-like state in adulthood,” Neuropsychopharmacology, vol. 34, no. 6, pp. 1609–1624, 2009. View at Publisher · View at Google Scholar · View at Scopus
  49. M. R. Zarrindast, N. Naghdi-Sedeh, M. Nasehi, H. Sahraei, F. Bahrami, and F. Asadi, “The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response,” Neuroscience Letters, vol. 475, no. 3, pp. 156–160, 2010. View at Publisher · View at Google Scholar · View at Scopus
  50. S. Weiss, M. Nosten-Bertrand, J. M. McIntosh, B. Giros, and M.-P. Martres, “Nicotine improves cognitive deficits of dopamine transporter knockout mice without long-term tolerance,” Neuropsychopharmacology, vol. 32, no. 12, pp. 2465–2478, 2007. View at Publisher · View at Google Scholar · View at Scopus
  51. F. Beiranvand, C. Zlabinger, A. Orr-Urtreger, R. Ristl, S. Huck, and P. Scholze, “Nicotinic acetylcholine receptors control acetylcholine and noradrenaline release in the rodent habenulo-interpeduncular complex,” British Journal of Pharmacology, 2014. View at Publisher · View at Google Scholar
  52. S. Zevin and N. L. Benowitz, “Drug interactions with tobacco smoking. An update,” Clinical Pharmacokinetics, vol. 36, no. 6, pp. 425–438, 1999. View at Publisher · View at Google Scholar · View at Scopus
  53. M. Haass, G. Richardt, T. Brenn, E. Schomig, and A. Schomig, “Nicotine-induced release of noradrenaline and neuropeptide Y in guinea-pig heart: role of calcium channels and protein kinase C,” Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 344, no. 5, pp. 527–531, 1991. View at Google Scholar · View at Scopus
  54. A. Kucinski, S. Wersinger, E. K. Stachowiak et al., “Neuronal nicotinic receptor agonists ameliorate spontaneous motor asymmetries and motor discoordination in a unilateral mouse model of Parkinson's disease,” Pharmacology Biochemistry and Behavior, vol. 111, pp. 1–10, 2013. View at Publisher · View at Google Scholar · View at Scopus
  55. M. Ohashi, A. Saitoh, M. Yamada, J. I. Oka, and M. Yamada, “Riluzole in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice,” Psychopharmacology, 2014. View at Publisher · View at Google Scholar
  56. C. Le Magueresse and E. Cherubini, “Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus,” Hippocampus, vol. 17, no. 4, pp. 316–325, 2007. View at Publisher · View at Google Scholar · View at Scopus
  57. N. Djulančić, V. Radojičić, and M. Srbinovska, “The influence of tobacco blend composition on carbon monoxide formation in mainstream cigarette smoke,” Arhiv za Higijenu Rada i Toksikologiju, vol. 64, no. 1, pp. 107–113, 2013. View at Publisher · View at Google Scholar · View at Scopus
  58. S. M. Bierbower and R. L. Cooper, “The mechanistic action of carbon dioxide on a neural circuit and NMJ communication,” Journal of Experimental Zoology A: Ecological Genetics and Physiology, vol. 319, no. 6, pp. 340–354, 2013. View at Publisher · View at Google Scholar · View at Scopus
  59. S. Nuutinen, E. Ekokoski, E. Lahdensuo, and R. K. Tuominen, “Nicotine-induced upregulation of human neuronal nicotinic α7-receptors is potentiated by modulation of cAMP and PKC in SH-EP1-hα7 cells,” European Journal of Pharmacology, vol. 544, no. 1–3, pp. 21–30, 2006. View at Publisher · View at Google Scholar · View at Scopus
  60. M. F. Ferrari, E. F. Coelho, K. L. Farizatto, G. Chadi, and D. R. Fior-Chadi, “Modulation of tyrosine hydroxylase, neuropeptide Y, glutamate, and substance P in ganglia and brain areas involved in cardiovascular control after chronic exposure to nicotine,” International Journal of Hypertension, vol. 2011, Article ID 216464, 9 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  61. C. Aydin, O. Oztan, and C. Isgor, “Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype,” Behavioural Brain Research, vol. 222, no. 2, pp. 332–341, 2011. View at Publisher · View at Google Scholar · View at Scopus
  62. C. Aydin, O. Oztan, and C. Isgor, “Vulnerability to nicotine abstinence-related social anxiety-like behavior: molecular correlates in neuropeptide Y, Y2 receptor and corticotropin releasing factor,” Neuroscience Letters, vol. 490, no. 3, pp. 220–225, 2011. View at Publisher · View at Google Scholar · View at Scopus
  63. M. L. Leret, J. A. San Millán, and M. T. Antonio, “Perinatal exposure to lead and cadmium affects anxiety-like behaviour,” Toxicology, vol. 186, no. 1-2, pp. 125–130, 2003. View at Publisher · View at Google Scholar · View at Scopus
  64. E. G. Moreira, I. Vassilieff, and V. S. Vassilieff, “Developmental lead exposure: behavioral alterations in the short and long term,” Neurotoxicology and Teratology, vol. 23, no. 5, pp. 489–495, 2001. View at Publisher · View at Google Scholar · View at Scopus