Table of Contents
Journal of Nanoscience
Volume 2014, Article ID 343467, 8 pages
Research Article

Curious Case of Bactericidal Action of ZnO

1Solid State and Structural Chemistry Unit (SSCU), Indian Institute of Science (IISc), Bangalore 560012, India
2Department of Chemistry, Central Research Laboratory, Gandhi Institute of Technology and Management (GITAM) University, Rushikonda, Visakhapatnam, Andhra Pradesh 530045, India

Received 1 July 2014; Revised 19 September 2014; Accepted 3 October 2014; Published 17 November 2014

Academic Editor: Irshad Hussain

Copyright © 2014 Somnath Ghosh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


ZnO nanoparticles (NPs) are well known for their bactericidal properties. Various mechanisms are proposed for their bactericidal activity. An ambiguity still prevails to know which mechanism or property is mainly influencing the bactericidal activity of ZnO NPs. The antibacterial properties of ZnO NPs were investigated against both Gram-positive and Gram-negative bacteria. Different ZnO samples with different degrees of surface oxygen vacancies were prepared from ZnO2. The surface oxygen vacancy and thereby reactive oxygen species (ROS) production in aqueous ZnO solution are quantified by photoluminescence (PL) and electron paramagnetic resonance (EPR) spin trapping experiments, respectively. Systematic experiments have been performed to validate a precise antibacterial mechanism of ZnO particle.