In Vitro Cytotoxicity of Nanoparticles: A Comparison between Particle Size and Cell Type

Table 1

Particle characterization.

Particles	Description	Average size	Size using TEM (nm)	Size in media (nm)	PDI	Zeta potential (mV)
Nano ZnO	Zinc oxide nanopowder	<100 nm	94.5 ± 7.7	253.6 ± 2.5	0.311 ± 0.003	17.50 ± 1.17
Micro ZnO	Zinc oxide	<5 µm	158.3 ± 9.8	391.2 ± 0.8	0.266 ± 0.006	−8.60 ± 3.29
Nano SiO2	Silicon dioxide nanopowder	<10–20 nm	19.1 ± 2.3	98.5 ± 11.1	0.241 ± 0.018	−36.74 ± 1.67
Micro SiO2	Silicon dioxide	~0.5–10 µm	530.9 ± 3.9	892.1 ± 16.7	0.172 ± 0.005	−33.21 ± 5.63

According to the manufacturer Sigma-Aldrich.
Using transmission electron microscopy.
Using Zeta PALS.
PDI: polydispersity index.