Table of Contents
Journal of Oral Diseases
Volume 2014 (2014), Article ID 168584, 8 pages
Review Article

Saliva: A Cutting Edge in Diagnostic Procedures

Department of Oral Pathology, Saveetha Dental College, Saveetha University, No. 162 Poonamalle High Road, Velapanchavadi, Chennai 600077, India

Received 5 April 2014; Revised 8 May 2014; Accepted 12 May 2014; Published 26 May 2014

Academic Editor: Atsushi Saito

Copyright © 2014 Senthamil Sindhu and Nithya Jagannathan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The ability to monitor the health and disease status of the patient through saliva is a highly desirable goal for the health professionals. Considering the microconcentration of salivary constituents, saliva is explored to be diagnostic tool as it also meets the demands for an inexpensive, noninvasive and easy to use screening method. The incorporation of salivary diagnostics into clinical practice is gaining reality and will be of diagnostic value in the prospective future. The investigative use of saliva is not being applied only in dental health but also in various other systemic disorders. The advent of molecular techniques is gaining attention and this has triggered its application as a specific and sensitive biomarker in proteomics, genomics, and transcriptomics. This review discusses the basics of salivary diagnostics, expectoration techniques, and its application in various local and systemic disorders.