Table of Contents
Journal of Oral Diseases
Volume 2014, Article ID 785615, 11 pages
Review Article

Clinical Relevance of the Advanced Microbiologic and Biochemical Investigations in Periodontal Diagnosis: A Critical Analysis

1Department of Periodontics & Oral Implantology, National Dental College & Hospital, Gulabgarh, Derabassi, District SAS Nagar, Mohali, Punjab 140507, India
2Department of Periodontics & Oral Implantology, M.N.D.A.V. Dental College & Hospital, Solan, Himachal Pradesh 173223, India

Received 5 May 2014; Accepted 16 October 2014; Published 17 November 2014

Academic Editor: Gul Atilla

Copyright © 2014 Vishakha Grover et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


New approaches to periodontal diagnosis, including advanced microbiologic, biochemical, and genetic tests, have been shown to provide the clinician with the information not available by traditional means. The purpose of a diagnostic test is to confirm, exclude, classify, or monitor disease to guide treatment. Their clinical value depends on whether the information they provide leads to improved patient outcomes. This can be assessed by randomized trials, which compare patient outcomes from the new diagnostic test versus the old test strategy. Being nonmandatory for marketing approval, such trials are not always feasible because of large sample sizes requirements. So, many diagnostic tests enter the practice without being critically analysed for any additional benefits. Effective diagnosis is just as essential as the selection of effective treatments for the success of periodontal therapy. So, the current paper aims to focus on the practical utility of this rapidly emerging plethora of periodontal diagnostic tools, emphasizing the critical issues surrounding the clinical application of microbiologic and biochemical investigations, employed for periodontal diagnosis.