Head and Neck Solitary Extramedullary Plasmacytoma

Table 2

Characteristics and treatment outcomes of 565 patients with extramedullary solitary plasmacytoma of the head and neck in 26 reported series and the present study [3–7, 10–30].

Authors (references)	Pts’ number	MCPS	M/F	Median age	RT dose (Gy)	LC (%)	PTMM (%)	OS rate
Bachar et al. [24]	68	SNT	41/27	—	35	—	23	76% (5 yr)
Bolek et al. [29]	10	—	—	—	43.2	100	54	80% (15 yr)
Chao et al. [11]	14	SNT, NPX	14/0	59	45	100	31	54% (10 yr)
Creach et al. [10]	18	—	16/2	64	50.4	100	11	31–82% (5 yr)
Galieni et al. [12]	16	—	—	54	—	92	15	78% (15 yr)
Hotz et al. [27]	14	—	—	—	—	86	14	—
Jyothirmayi et al. [3]	7	SNT	6/1	58	40	85	42	57%
Kapadia et al. [13]	20	SNT, NPX	16/5	59	40–45	85	20	85% (10 yr)
Kilciksiz et al. [14]	23	Oral cavity	14/9	47	50	95	17.4	89% (10 yr)
Krause et al. [15]	8	NPX	—	61	48	100	25	100 (10 yr)
Liebross et al. [28]	19	—	—	—	50	95	44	50% (5 yr)
Mendenhall et al. [4]	20	SNT, NPX	17/3	62	40–50	100	30	80% (5 yr)
Michalaki et al. [16]	10	SNT	6/4	55	40–50	100	20	50% (5 yr)
Miller et al. [17]	18	SNT, NPX	12/6	50.4	45–50	—	11	—
Ozsahin et al. [26]	52	SNT	—	—	40	74	36	72% (5 yr)
Reed et al. [23]	23	SNT	—	56	45	92	30	85% (5 yr)
Sasaki et al. [18]	67	SNT	43/24	64	50	87	12	56% (10 yr)
Shih et al. [5]	10	—	9/1	63	54	70	20	100% (10 yr)
Strojan et al. [25]	22	Oropharynx	17/5	—	54	100	8	61% (10 yr)
Suh et al. [19]	13	SNT	8/5	52	50	77	15	87% (10 yr)
Susnerwala et al. [7]	25	SNT	23/2	68	38.9	79	8	59% (5 yr)
Tournier-Rangeard et al. [21]	17	SNT, NPX	14/3	62	52.6	73	31	63.4% (10 yr)
Tsang et al. [6]	14	SNT, NPX	—	—	35	93	84	65% (10 yr)
Yang et al. [20]	23	SNT	17/6	49	—	—	—	—
Yang et al. [30]	8	—	—	—	35	—	12.5	—
Zhou et al. [22]	12	SNT	10/2	57	—	—	—	53% (5 yr)
Present study	13	SNT, NPX	10/3	52	49	89	15	74.1% (10 yr)
Total	564	SNT	293/108	58	44.5	88	23	70

Pts’ number: patients number, MCST: most common primary sites, M/F: male/female, LC: local recurrence, PTMM: progressed to multiple myeloma, OS: overall survival, SNT: sinonasal tract, NPX: nasopharynx, LRX: larynx, and NC: nasal cavity.