Table 1: Mapping between the biological immune system and SCMIA.

Biological Immune SystemSCMIA

Antigen (Ag)Objective function (simulation model in simulation study) to be optimized
Antibody (Ab)Candidate solution (a set of decision variables) to be optimized
Ag-Ab affinityFitness value of each candidate solution evaluated based on Pareto dominance
Ab-Ab affinityCrowding-distance proposed by Deb et al. [6] working as a measure of population diversity
Immune suppressionMechanism to control the number of nearby candidate solutions based on similarity among candidate solutions in both the objective space and decision variable space
Memory cellCurrent best nondominated solution