Microencapsulation for the Therapeutic Delivery of Drugs, Live Mammalian and Bacterial Cells, and Other Biopharmaceutics: Current Status and Future Directions

Table 2

Microencapsulated microorganism formulations for therapeutic applications.

Disease condition	Microcapsule type	Encapsulated cells type	Delivery method and models	Reference(s)
	APA	E. coli DH5	In vitro	[2]
	APA	E. coli DH5	Rat intragastric gavage	[2]
	APA	E. coli DH5	Rat intramuscular injection	[3]
Renal diseases	Polyvinyl alcohol	E. coli DH5	In vitro	[4]
	APA	Saccharomyces cerevisiae	Rat intragastric gavage	[5]
	Alginate chitosan alginate	E. coli DH5	In vitro	[6]
	Alginate chitosan alginate	E. coli DH5	Rat douche	[6]
	Alginate chitosan	Lactobacillus acidophilus	In vitro	[7]
	APA	Lactobacillus delbrueckii	In vitro	[8]
	Alginate and alginate-polylysine	Pseudomonas pictorum	In vitro	[9]
	APA	Lactobacillus plantarum 80 (pCBH1)	In vitro	[10]
	APA	Lactobacillus fermentum	Hamster intragastric gavage	[11]
Cardiovascular diseases	APA	Bifidobacterium longum	In vitro	[12]
	APA	Lactobacillus reuteri	In vitro	[12]
	APA	Lactobacillus reuteri	Human, incorporated in yogurt	[13]
	APA	Lactobacillus fermentum	In vitro	[14]
	APA	Lactobacillus fermentum	Hamster intragastric gavage	[15]
Colorectal cancer	APA	Lactobacillus acidophilus	Mouse intragastric gavage	[16]
	Alginate-chitosan	Lactobacillus acidophilus	In vitro	[7]
Inflammatory bowel syndrome/ inflammatory bowel disease	APA	Lactobacillus acidophilus	Mouse intragastric gavage	[17]
	Alginate	Bifidobacterium longum	In vitro	[18]
		Bifidobacterium lactis
	Alginate	Bifidobacterium longum	In vitro	[19]
Others		Bifidobacterium longum
	Gelatin	Bifidobacterium bifidum	Rat intragastric gavage	[20]
		Bifidobacterium adolescentis
	Reconstituted skim milk with prebiotics	Bifidobacterium BB-12	In vitro	[21]