Pentoxifylline Loaded Floating Microballoons: Design, Development and Characterization

Table 2

Characterization of pentoxifylline loaded microballoons.

Parameters	Formulation code
	F1	F2	F3	F4	F5	F6
Particle size (𝜇m)^a	74.63±1.04	85.18±3.12	104.0±2.87	82.96±2.13	99.32±1.45	110.4±2.94
Production yield (%)^a	75.76±1.54	78.13±1.21	80.89±2.24	76.79±1.38	74.66±2.61	72.57±1.85
Incorporation efficiency (%)^a	75.5±1.82	76.36±1.27	77.85±0.61	76.22±0.82	77.29±0.12	77.66±1.35
Buoyancy (%)^a	72.43±0.21	74.28±1.82	77.52±2.04	73.64±1.73	76.24±0.82	78.19±0.63
In vitro drug release (%)^a	96.81±0.16	88.84±0.46	82.21±1.29	93.13±1.48	90.16±0.98	87.09±1.73

^aEach value indicates the mean ± SD (𝑛=3).