Research Article
Preparation and Comparative Bioavailability Studies of Indomethacin-Loaded Cetyl Alcohol Microspheres
Table 4
Comparison of mean values of pharmacokinetics obtained for products Microcid SR and formulation F3 after oral administration.
| | Parameters* | Microcid SR | Formulation F3 | value |
| | (h) | 3.0 | 2.9 | >0.05 | | (ng/mL) | 2134 ± 29.60 | 1989 ± 20.30 | >0.05 | | (h−1) | 2.62 ± 0.02 | 2.67 ± 0.20 | >0.05 | | (ng/mL h−1) | 12478 ± 104.21 | 12145 ± 87.32 | >0.05 | | (ng/ML h−1) | 12632 ± 132.12 | 12452 ± 96.32 | >0.05 | | (h−1) | 0.3934 ± 0.002 | 0.3856 ± 0.002 | >0.05 | | (h−1) | 0.2843 ± 0.004 | 0.2678 ± 0.004 | >0.05 | | Mean residence Time (MRT) | 4.89 ± 0.03 | 4.75 ± 0.03 | >0.05 |
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*Mean ± standard deviation, .
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