Journal of Pharmaceutics / 2013 / Article / Fig 2

Research Article

Transdermal Delivery of Small Interfering RNA with Elastic Cationic Liposomes in Mice

Figure 2

The suppression of luciferase activity (a) and cytotoxicity (b) after siRNA transfection by elastic cationic liposomes. In (a), cationic lipoplexes were added to FL-SiHa cells at 50 nM siRNA. The luciferase assay was carried out 48 h after incubation of the lipoplexes. Statistical significance was evaluated by Student’s -test. , , and , compared with lipoplex of Cont siRNA. In (b), cytotoxicity was evaluated 48 h after transfection. In (a) and (b), each column represents the mean ± S.D. .

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