Cellular Redox Status Regulates Emodin-Induced Radiosensitization of Nasopharyngeal Carcinoma Cells In Vitro and In Vivo

Table 6

Maximum tumor diameter doubling time and tumor growth delay associated with different treatments (𝑥±𝑠, 𝑛=6).

Group	Maximum tumor diameter doubling time/day	Tumor growth delay/day	Enhancement factor/%
Control group	17.02 ± 1.12	—
Solvent group	17.14 ± 0.63	0.12
Low-dose emodin (4 mg/kg)	17.20 ± 0.84	0.20
High-dose emodin (12 mg/kg)	17.40 ± 1.01	0.40
radiotherapy group	21.30 ± 1.14*	4.28
Low-dose emodin + 2 Gy	24.10 ± 0.72**	6.90	1.612
High-dose emodin + 2 Gy	25.17 ± 0.64**	8.15	1.904

^∗𝐹 = 4.318, P < 0.05, Radiotherapy group compared to control group, **𝐹 = 2.163, P < 0.05, combined group versus simple radiotherapy group.