Journal of Pharmaceutics / 2013 / Article / Tab 5

Research Article

Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design

Table 5

Dissolution model for to formulations.

Batch codeRelease exponent (n)Kinetic constant (K)R Best fit model

0.5919 30.8556 0.9874 Matrix
0.5030 36.2863 0.9828 Matrix
0.5171 31.8826 0.9845 Matrix
0.5008 29.6438 0.9870 Matrix
0.5301 27.1364 0.9897 Matrix
0.5814 36.9647 0.9955 Matrix
0.5049 36.9443 0.9957 Matrix

Non-Fickian.

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