Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design
Table 5
Dissolution model for to formulations.
Batch code
Release exponent (n)
Kinetic constant (K)
R
Best fit model
0.5919
30.8556
0.9874
Matrix
0.5030
36.2863
0.9828
Matrix
0.5171
31.8826
0.9845
Matrix
0.5008
29.6438
0.9870
Matrix
0.5301
27.1364
0.9897
Matrix
0.5814
36.9647
0.9955
Matrix
0.5049
36.9443
0.9957
Matrix
Non-Fickian.
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