Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design
Table 7
Composition of optimum formulations , , and .
Composition (mg)
Formulations
Tramadol HCl
100
100
100
Carboxymethyl xyloglucan
194.39
190.606
200
HPMC-K-100M
15.610
19.394
10
DCP
30
30
30
Talc
5
5
5
Magnesium stearate
5
5
5
PVP K-30
30
30
30
Isopropyl alcohol
qs.
qs.
qs.
We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.