Simultaneous Determination of Clidinium Bromide and Chlordiazepoxide in Combined Dosage Forms by High-Performance Liquid Chromatography

Table 5

Stability study for the drug in different formulations.

Product^a	Time (days)	Amount found^b (mg)		% Recovery		%  ±RSD
		CDB	CDZ	CDB	CDZ	CDB	CDZ
	0	2.51	5.04	100.40	100.80	1.91	0.22
Ribax capsules	1	2.52	5.05	100.80	101.00	0.98	0.49
	5	2.50	5.02	100.00	100.40	0.32	0.74
	10	2.49	5.01	99.60	100.20	1.05	0.86
	0	2.56	5.03	102.40	100.60	0.49	0.29
Laberax tablets	1	2.55	5.05	102.00	101.00	0.53	0.36
	5	2.51	5.04	100.40	100.80	0.82	0.40
	10	2.52	5.01	101.80	100.20	0.75	0.29
	0	2.58	5.01	103.20	100.20	1.13	0.31
Librax tablets	1	2.55	5.00	102.00	100.00	0.97	0.91
	5	2.53	4.99	101.20	99.80	0.68	0.87
	10	2.54	4.98	101.60	99.60	0.81	0.95

a The dose is 2.5 mg CDB and 5.0 mg CDZ for all products.
^bFive independent analyses.