Quantification of Lumefantrine in Human Plasma Using LC-MS/MS and Its Application to a Bioequivalence Study

Table 2

Recovery for lumefantrine and artesunate (n = 6).

Analytes	Level	𝐴	𝐵	% Recovery	% CV
Lumefantrine	LQC	17238	15995	92.85	4.51
	MQC	271999	251471	92.47	3.05
	HQC	440485	414535	94.15	3.55
Artesunate	LQC	226450	200282	88.50	2.90
	MQC	214968	196401	91.37	1.55
	HQC	210154	195829	93.27	4.59

𝐴: mean area of unextracted sample (𝑛=6); 𝐵: mean area of extracted sample (𝑛=6); mean recovery was found to be 93.16% for lumefantrine and 91.05 for artesunate; CV: coefficient of variation.