Quantification of Lumefantrine in Human Plasma Using LC-MS/MS and Its Application to a Bioequivalence Study

Table 4

Pharmacokinetic parameters of lumefantrine using non-compartmental analyses.

Parameters	Lumefantrine
	Mean ± SD
	Test	Reference
𝐶max (ng/mL)	4048.66 ± 511.45	4119.53 ± 475.21
AUC0–72 (ng × h/mL)	26665.94 ± 9199.99	26461.79 ± 8578.98
𝑇max (h)	1.60 ± 0.34	1.57 ± 0.32
𝐾el (h^−1)	0.03 ± 0.02	0.03 ± 0.02
𝑇1/2 (h)	40.05 ± 23.72	34.78 ± 23.63