Optimization of Metronidazole Emulgel

Table 6

Composition of checkpoint formulations, the predicted, and experimental values of response variables and percentage prediction error.

Formulation code	Composition (%w/w)	Response	Predicted; value	Experimental value	Percentage; error
O1	10*	Release (%)	93.20	92.45	−0.80
	55^#	Spreadability	24.27	23.97	−0.98
	1^$
O2	10*	Release (%)	93.16	93.48	+0.12
	30.85^#	Spreadability	24.26	23.91	−1.04
	1^$
O3	0.9*	Release (%)	93.16	93.08	−0.23
	47.73^#	Spreadability	24.23	23.90	−1.36
	1^$

*Concentration of oil, ^#concentration of 𝑆_mix, and ^$concentration of gelling agent.