Development of Orodispersible Tablets of Candesartan Cilexetil-β-cyclodextrin Complex

Table 1

Formulation table for ODT’s using complexes prepared by kneading method.

Formulations	Ingredients (mg) Total tablet weight = 150 mg
	Candesartan-β-cyclodextrin complex	Mannitol	Low HPC	Crospovidone	Croscarmellose sodium	Sodium starch glycolate	Aspartame	Aerosil	Talc
F1	82	49	5	—	—	—	5	3	6
F2	82	46.5	7.5	—	—	—	5	3	6
F3	82	44	10	—	—	—	5	3	6
F4	82	49	—	5	—	—	5	3	6
F5	82	46.5	—	7.5	—	—	5	3	6
F6	82	44	—	10	—	—	5	3	6
F7	82	49	—	—	5	—	5	3	6
F8	82	46.5	—	—	7.5	—	5	3	6
F9	82	44	—	—	10	—	5	3	6
F10	82	49	—	—	—	5	5	3	6
F11	82	46.5	—	—	—	7.5	5	3	6
F12	82	44	—	—	—	10	5	3	6