Research Article
Study on Mixed Solvency Concept in Formulation Development of Aqueous Injection of Poorly Water Soluble Drug
Table 7
Chemical stability data of formulation F8.
| Formulation code | Temperature | Concentration* mg/vials |
Degradation | 0 day | 7 day | 15 day | 30 day |
| | 4 ± 2°C | 80.04 ± 0.012 | 79.41 ± 0.013 | 79.03 ± 0.011 | 79.06 ± 0.014 | 1.18% | F8 | 37 ± 2°C | 80.04 ± 0.012 | 79.22 ± 0.011 | 78.94 ± 0.014 | 78.87 ± 0.020 | 1.42% | | 60 ± 2°C | 80.04 ± 0.009 | 78.84 ± 0.021 | 78.47 ± 0.019 | 78.59 ± 0.012 | 1.77% |
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Average of 3 determinations.
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