Research Article

Quantum Dot-Loaded Liposomes to Evaluate the Behavior of Drug Carriers after Oral Administration

Figure 3

CLSM images and cytotoxicity study of Caco-2 cells following a 1h uptake of hydrophobic (unmodified) QD-loaded liposomal preparations: (a) SA liposomes (positive zeta potential) and (b) DCP liposomes (negative zeta potential). The QD concentration was 800 nM. Scale bars represent 20 μm. (c) Cytotoxic side effects of QD-loaded SA liposomes at QD concentrations ranging from 0 to 800 nM on Caco-2 cells at 37°C. The liposomal exposure time of cells was 2 h. The viability of treated cells was determined by the MTS assay. Symbols represent the mean ± standard deviation ( ).
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(a) SA liposome
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(b) DCP liposome
848275.fig.003c
(c) Cytotoxicity