Development and Evaluation of Dual Cross-Linked Pulsatile Beads for Chronotherapy of Rheumatoid Arthritis

Table 3

Characteristics of composite pectin alginate beads.

Batch code	Production yield (%)	Entrapment efficiency	Average diameter (mm)	% Swelling (6.8 pH)	% Swelling (1.2 pH)
P1	85.30 ± 0.70	82.95 ±1.42	1.15 ± 0.06	200.5 ± 32.4	31.5 ± 12.3
P2	91.38 ± 1.26	72.93 ± 1.20	1.08 ± 0.05	175.3 ± 27.0	40.8 ± 9.70
P3	87.69 ± 2.39	74.89 ± 1.32	1.06 ± 0.07	158.9 ± 19.5	42.3 ± 13.0
P4	91.49 ± 1.63	79.37 ± 1.55	1.11 ± 0.06	293.8 ± 20.5	24.2 ± 9.13
P5	88.41 ± 0.57	76.69 ± 3.57	1.07 ± 0.05	114.4 ± 22.6	55.2 ± 12.6
P6	93.30 ± 0.76	83.24 ± 1.05	1.30 ± 0.03	57.0 ± 5.1	29.4 ± 9.21
P7	92.70 ± 1.46	83.04 ± 1.57	1.20 ± 0.03	72.6 ± 9.4	25.5 ± 5.49
P8	88.36 ± 1.37	80.65 ± 1.95	1.16 ± 0.04	98.6 ± 11.25	25.6 ± 3.55
P9	90.69 ± 0.98	83.01 ± 1.36	1.18 ± 0.07	81.54 ± 6.28	28.7 ± 5.11