Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Vesicle type</td><td align="center"><svg height="15.4" id="M8" style="vertical-align:-3.3907pt" version="1.1" viewbox="0 0 20.5375 15.4" width="20.5375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><path d="M780 372q0 -191 -178 -297q-128 -75 -335 -75h-250l7 27q61 7 77 22t28 76l77 398q11 62 0 76.5t-77 22.5l6 28h292q164 0 258.5 -67.5t94.5 -210.5zM678 375q0 119 -73 180.5t-201 61.5q-62 0 -82 -13q-17 -7 -25 -53l-80 -427q-8 -47 -4 -62t26 -20q24 -6 80 -6
q166 0 262.5 95t96.5 244z" id="x1D437"></path></g>
<g transform="matrix(.012,-0,0,-.012,13.712,15.187)"><path d="M499 88q-41 -46 -83.5 -73t-68.5 -27q-41 0 -19 98l52 225q10 43 8 59.5t-16 16.5q-37 0 -112 -65t-117 -135q-14 -42 -38 -179q-36 -7 -75 -20l-7 8l127 594q8 40 2.5 49t-35.5 9h-35l5 25q36 3 71.5 13t56.5 18t25 8q11 0 3 -38l-88 -417h2q77 102 195 167q44 24 79 24
q61 0 30 -130l-52 -220q-8 -33 4 -33q8 0 31 14.5t43 33.5z" id="x210E"></path></g>
</svg> (nm)</td><td align="center">Polydispersity</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">PolyGem</td><td align="center">180 ± 12</td><td align="center">0.146 ± 0.045</td></tr><tr><td align="left">Blank polymersome</td><td align="center">181 ± 13</td><td align="center">0.113 ± 0.023</td></tr><tr><td align="left">PZn<sub>3</sub>-polymersome</td><td align="center">180 ± 31</td><td align="center">0.163 ± 0.020</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Hydrodynamic diameter and polydispersity of different vesicle formulations.

Journal of Pharmaceutics

tab1

Table 1

Table 1: Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells 