Development and Evaluation of Novel Self-Nanoemulsifying Drug Delivery Systems Based on a Homolipid from Capra hircus and Its Admixtures with Melon Oil for the Delivery of Indomethacin

Table 3

Emulsification time of batches of indomethacin-loaded SNEDDS.

Batch*	Ratio of oil blend : surfactant blend : cosurfactant**	Mean time ± S.E.M. (min)
1A	20 : 60 : 20	1.54±0.22
1B	20 : 60 : 20	2.89±0.16
1C	20 : 60 : 20	1.85±0.14
1D	20 : 60 : 20	3.52±0.28
2A	35 : 45 : 20	0.44±0.15
2B	35 : 45 : 20	2.35±0.23
2C	35 : 45 : 20	0.58±0.08
2D	35 : 45 : 20	3.63±0.22
3A	25 : 55 : 20	1.03±0.25
3B	25 : 55 : 20	3.13±0.20
3C	25 : 55 : 20	1.18±0.33
3D	25 : 55 : 20	3.33±0.25
4A	25 : 60 : 15	1.30±0.28
4B	25 : 60 : 15	2.86±0.18
4C	25 : 60 : 15	1.54±0.37
4D	25 : 60 : 15	3.79±0.34

∗A contains goat fat, B contains goat fat and carbosil, C contains goat fat with melon oil, and D contains goat fat with melon oil and carbosil. **All batches contain lipid (either goat fat or a 1 : 1 blend of goat fat with melon oil), surfactant (1 : 1 blend of Tween 60 and Tween 80), and Span 85 combined in the ratio shown above.