Research Article

The Population Pharmacokinetic Models of Tacrolimus in Chinese Adult Liver Transplantation Patients

Table 1

Characteristics of the 47 adult patients (27 male/20 female).

CharacteristicsMeanSDMedianRange

Gender (male/female)(27/20)

Age (y)57.4711.166025–78
Dose (mg/d)5.312.2751–10.5
Postoperative days (d)20.7118.04142–85
Alkaline phosphatase (IU/L)108.161.2298.323.5–385.6
Alanine amino transferase (IU/L)105.899.172.29.8–72.2
Aspirate amino transferase (IU/L)41.3839.6229.99.6–332.1
Total bilirubin ( mol/L)47.0260.5527.472.82–436.7
Serum creatinine ( mol/L)92.9580.3767.525.9–520.3
Haemotocrit (%)28.945.7282–83.4
White blood cell (*109/L)7.853.857.321.52–41.1
Red blood cell (*1012/L)3.230.733.072–8.99