Development of Budesonide Loaded Biopolymer Based Dry Powder Inhaler: Optimization, In Vitro Deposition, and Cytotoxicity Study

Table 1

Factorial design of all formulations.

Formulation	Factorial design	Calcium chloride (mL)	Chitosan (mg)
F1	(−1, −1)	1	2
F2	(−1, 0)	1	3
F3	(−1, +1)	1	4
F4	(0, −1)	2	2
F5	(0, 0)	2	3
F6	(0, +1)	2	4
F7	(+1, −1)	3	2
F8	(+1, −1)	3	3
F9	(+1, +1)	3	4