Preparation and In Vitro Evaluation of Ethylcellulose and Polymethacrylate Resins Loaded Microparticles Containing Hydrophilic Drug

Table 1

Batch yield, entrapment efficiency, drug content, and size of prepared microparticles.

Polymer grade	Code	Ratio	% yield	Encapsulation efficiency	Drug content	Particle size (𝜇m)
EC 300	F1	1 : 1	91.6±0.5	83.7±0.6	45.9±0.3	139±13
	F2	1 : 3	94.0±0.4	87.7±0.6	23.7±0.5	261±24
	F3	1 : 5	95.8±0.3	93.7±0.6	16.7±0.5	388±32
	F4	1 : 7	98.6±0.6	96.7±0.5	12.8±0.4	580±56
RS 100	F5	1 : 1	57.6±0.6	68.6±0.6	60.0±0.3	133±14
	F6	1 : 3	63.9±0.2	73.7±0.5	29.0±0.3	246±38
	F7	1 : 5	71.6±0.7	77.8±0.7	18.6±0.5	368±43
	F8	1 : 7	76.8±0.3	83.7±0.6	16.8±0.5	464±44
RL 100	F9	1 : 1	62.6±0.5	73.9±0.8	59.3±0.2	142±28
	F10	1 : 3	67.6±0.6	79.7±0.6	29.9±0.3	263±42
	F11	1 : 5	85.2±0.2	84.7±0.6	16.9±0.3	379±49
	F12	1 : 7	89.0±0.1	89.7±0.6	12.9±0.4	508±58