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Journal of Pharmaceutics
Volume 2015 (2015), Article ID 828453, 8 pages
http://dx.doi.org/10.1155/2015/828453
Research Article

Enhancement of Solubility of Lamotrigine by Solid Dispersion and Development of Orally Disintegrating Tablets Using 32 Full Factorial Design

Department of Pharmaceutics, ASBASJSM College of Pharmacy, BELA, Ropar, Punjab 140111, India

Received 16 July 2015; Accepted 11 October 2015

Academic Editor: Fabiana Quaglia

Copyright © 2015 Jatinderpal Singh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Mohapatra, R. K. Parikh, and M. C. Gohel, “Formulation, development and evaluation of patient friendly dosage forms of metformin. Part-I. Orally disintegrating tablets,” Asian Journal of Pharmaceutics, vol. 2, no. 3, pp. 167–171, 2008. View at Publisher · View at Google Scholar
  2. J. J. Hirani, D. A. Rathod, and K. R. Vadalia, “Orally disintegrating tablets: a review,” Tropical Journal of Pharmaceutical Research, vol. 8, no. 2, pp. 161–172, 2009. View at Google Scholar · View at Scopus
  3. J. Xu, L. L. Bovet, and K. Zhao, “Taste masking microspheres for orally disintegrating tablets,” International Journal of Pharmaceutics, vol. 359, no. 1-2, pp. 63–69, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. W. Habib, R. Khankari, and J. Hontz, “Fast-dissolve drug delivery systems,” Critical Reviews in Therapeutic Drug Carrier Systems, vol. 17, no. 1, pp. 61–72, 2000. View at Google Scholar · View at Scopus
  5. S. V. Sastry, J. R. Nyshadham, and J. A. Fix, “Recent technological advances in oral drug delivery—a review,” Pharmaceutical Science and Technology Today, vol. 3, no. 4, pp. 138–145, 2000. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. Fu, S. Yang, S. H. Jeong, S. Kimura, and K. Park, “Orally fast disintegrating tablets: developments, technologies, taste-masking and clinical studies,” Critical Reviews in Therapeutic Drug Carrier Systems, vol. 21, no. 6, pp. 433–475, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Bandari, R. K. Mittapalli, R. Gannu, and Y. M. Rao, “Orodispersible tablets: an overview,” Asian Journal of Pharmaceutics, vol. 2, no. 1, pp. 2–11, 2008. View at Publisher · View at Google Scholar
  8. L. Mali Sandip, B. Nighute Ashok, D. Vivek, D. Gonjari Indrajeet, and B. Bhise Satish, “Microcrystals: for improvement of solubility and dissolution rate of Lamotrigine,” International Journal of Pharmaceutical Sciences, vol. 2, no. 2, pp. 515–521, 2010. View at Google Scholar · View at Scopus
  9. H. J. Shah, G. Subbaiah, D. M. Patel, and C. N. Patel, “In vitro-in vivo correlation of modified release dosage form of lamotrigine,” Biopharmaceutics & Drug Disposition, vol. 30, no. 9, pp. 524–531, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. P. P. Amrutkar, S. B. Patil, A. N. Todarwal, M. A. Wagh, P. D. Kothawade, and R. K. Surawase, “Design and evaluation of taste masked chewable dispersible tablet of lamotrigine by melt granulation,” International Journal of Drug Delivery, vol. 2, no. 2, pp. 183–191, 2010. View at Publisher · View at Google Scholar
  11. S. T. Birhade, V. H. Bankar, P. D. Gaikwad, and S. P. Pawar, “Preparation and evaluation of cyclodextrin based binary systems for taste masking,” International Journal of Pharmaceutical Research and Development, vol. 2, no. 3, pp. 199–203, 2010. View at Google Scholar
  12. H. Goel, P. Rai, V. Rana, and A. K. Tiwary, “Orally disintegrating systems: innovations in formulation and technology,” Recent Patents on Drug Delivery and Formulation, vol. 2, no. 3, pp. 258–274, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Garg and G. D. Gupta, “Preparation and evaluation of gastroretentive floating tablets of acyclovir,” Current Drug Delivery, vol. 6, no. 5, pp. 437–443, 2009. View at Publisher · View at Google Scholar
  14. A. Modi and P. Tayade, “Enhancement of dissolution profile by solid dispersion (kneading) technique,” AAPS PharmSciTech, vol. 7, no. 3, pp. E87–E92, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. R. L. Shid, S. N. Dhole, N. Kulkarni, and S. L. Shid, “Formulation and evaluation of nanosuspension delivery system for simvastatin,” International Journal of Pharmaceutical Sciences and Nanotechnology, vol. 7, pp. 2459–2476, 2014. View at Google Scholar
  16. L. Shan-Yang and K. Yuh-Horng, “Solid particulates of drug-β-cyclodextrin inclusion complexes directly prepared by a spray-drying technique,” International Journal of Pharmaceutics, vol. 56, no. 3, pp. 249–259, 1989. View at Publisher · View at Google Scholar · View at Scopus
  17. Y. S. R. Krishanaiah, K. Latha, L. Nageswara Rao, R. S. Karthikeyan, P. Bhaskar, and V. Satyanarayana, “Development of colon targeted oral guar gum matrix tablets of Albendazole for the treatment of helminthiasis,” Indian Journal of Pharmaceutical Sciences, vol. 65, no. 4, pp. 378–385, 2003. View at Google Scholar · View at Scopus
  18. Her Majesty's Stationary Office, British Pharmacopoeia, vol. 2, Her Majesty's Stationary Office, London, UK, 2000.
  19. C. M. Setty, M. Radhika, V. R. M. Gupta, M. V. R. Reddy, and A. V. Jithan, “Effect of tablet processing and formulation factors on disintegration and dissolution of aceclofenac tablets,” International Journal of Pharmaceutical Sciences and Nanotechnology, vol. 3, no. 4, pp. 1240–1251, 2011. View at Google Scholar